Is Palmitoyl Pentapeptide-4 Natural?

Q: Is Palmitoyl Pentapeptide-4 natural?

Palmitoyl Pentapeptide-4 has a Natural Origin Index (NOI) of 0.00 (scale 0–1) per ISO 16128. Palmitoyl Pentapeptide-4 is synthesized through a multi-step process involving amino acid coupling and subsequent acylation, with the primary feedstocks and reagents being petro… An NOI of 0.00 means 0% of its molecular mass is traceable to a natural, renewable source.

Learn about Palmitoyl Pentapeptide-4 — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.

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Natural Origin Index

INCI NamePalmitoyl Pentapeptide-4

IUPAC Name(2S)-2-[[(2S)-6-amino-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoic acid

FormulaC39H75N7O10

PubChem CID9897237 ↗

FunctionSkin Conditioning Agent · Peptide

FeedstockThe primary feedstocks for Palmitoyl

Chemical Structure

2D structure of Palmitoyl Pentapeptide-4

Learn about Palmitoyl Pentapeptide-4 — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.

View full data on PubChem ↗

Quick Facts

INCI NamePalmitoyl Pentapeptide-4
IUPAC Name(2S)-2-[[(2S)-6-amino-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoic acid
Molecular FormulaC39H75N7O10
PubChem CID9897237 ↗
FunctionsSkin Conditioning AgentPeptide
Primary FeedstockThe primary feedstocks for Palmitoyl Pentapeptide-4 are derived from petrochemical sources. This includes the amino acids (lysine, methionine, proline, serine) which are typically synthesized via complex organic chemistry routes starting from basic petrochemical building blocks. The palmitic acid moiety is also commonly derived from petrochemical sources, although plant-derived palmitic acid is also available.
NOI Score0.0 / 1.0
Tier100% Petroleum

Description

Learn about Palmitoyl Pentapeptide-4 — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.

References

1ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products — Part 2. ISO, Geneva.
2Palmitoyl Pentapeptide-4. National Center for Biotechnology Information. PubChem CID 9897237. pubchem.ncbi.nlm.nih.gov ↗