Is Azelaic Acid Natural?

Q: Is Azelaic Acid natural?

Azelaic Acid has a Natural Origin Index (NOI) of 0.60 (scale 0–1) per ISO 16128. The primary commercial route for Azelaic Acid involves the ozonolysis of oleic acid, a naturally derived fatty acid, resulting in a mostly renewable NOI. An NOI of 0.60 means 60% of its molecular mass is traceable to a natural, renewable source.

Learn about Azelaic Acid — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.

0.6

out of 1.0

Natural Origin Index

INCI NameAzelaic Acid

IUPAC Namenonanedioic acid

FormulaC9H16O4

PubChem CID2266 ↗

FunctionSkin Conditioning Agent · Antioxidant

FeedstockThe primary commercial feedstock for

Chemical Structure

Learn about Azelaic Acid — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.

View full data on PubChem ↗

Quick Facts

INCI NameAzelaic Acid
IUPAC Namenonanedioic acid
Molecular FormulaC9H16O4
PubChem CID2266 ↗
FunctionsSkin Conditioning AgentAntioxidantExfoliant
Primary FeedstockThe primary commercial feedstock for Azelaic Acid is oleic acid, a monounsaturated fatty acid commonly derived from vegetable oils such as olive oil, sunflower oil, or canola oil. While other synthesis routes exist, the ozonolysis of oleic acid is the most prevalent method for producing cosmetic-grade Azelaic Acid.
NOI Score0.6 / 1.0
TierMostly Renewable

Description

Learn about Azelaic Acid — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.

References

1ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products — Part 2. ISO, Geneva.
2Azelaic Acid. National Center for Biotechnology Information. PubChem CID 2266. pubchem.ncbi.nlm.nih.gov ↗